Types of cancer-causing genetic alterations, and examples:
Cell cycle control genes.
APC (adenomatous polyposis coli ) gene is mutated in about 80% of colorectal cancers
APC protein mutations incapacitate the complex that degrades beta-catenin (Wnt signaling pathway).
Cell growth and division are controlled by multiple mechanisms, therefore there are many possible mechanisms for producing a final cancerous cell.
For review questions and answers: https://quizlet.com/388776589
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