Cell cycle consists of M-phase, G1, (G0), S, G2. G0 is a dormant phase that may or may not be present.
BRDU (bromo-deoxyuridine) staining
General DNA stains and flow cytometry
Common molecular features of cell cycle control systems:
Mechanism of Cell Cycle Progression
Main drivers are “Cyclin-dependent kinases” (Cdks), which are activated by synthesis and degradation of proteins called cyclins.
Since the expression level of cell cycle proteins plays a critical role in regulating the cell cycle, it is not surprising that specific protein degradation mechanisms are involved in different places in the cell cycle.
The Metaphase/Anaphase Transition is a good example:
Protein kinases and phosphatases that modify Cdks
For review questions and answers: https://quizlet.com/388776589
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